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Lipitor Goes Generic, As Good as Crestor, But Pfizer Markets to Extend Brand Revenues

December 12, 2011 By: Nadia Category: Cholesterol, HealthCare, Medicine Advice, Medtipster, Prescription News, Prescription Savings

www.Medtipster.com Source: USA Today, 11/15/2011

On November 30, 2011, the cholesterol medication Lipitor (atorvastatin) converted to generic status. For the first six months, two companies, Watson Pharmaceuticals, Inc. and Ranbaxy Laboratories, Ltd., will produce the generic. After May 2012, several generic manufacturers are expected to enter the market.

Pfizer Inc., the maker of Lipitor is marketing hard for people to keep buying its brand-name version for the next 6 months. Pfizer is offering

  • patients a discount card to get Lipitor for $4 a month, and
  • rebates to insurance companies that cover Lipitor for the next 6 months.

This action by Pfizer will result in the costs of Lipitor being below generic prices and Pfizer will get 70% of the proceeds from one of the two versions sold now.

USA Today reported, that large doses of Lipitor and Crestor did about equally well according to a study of 1,385 patients presented at the annual meeting of the American Heart Association in Orlando. Crestor, made by AstraZeneca, “will be the last major statin not on patent,” said Cam Patterson, chief of cardiology at the University of North Carolina-Chapel Hill, who was not involved in the study. “The market for Crestor will go close to zero.”

Study findings

At the end of the two-year study,

  • Two-thirds of patients had less plaque in their arteries.
  • Both statins shrunk the size of plaque in the coronary artery by about 1%.
  • Patients on Crestor had a low-density lipoprotein (LDL) level of 63 milligrams per deciliter, while those who took Lipitor had a level of 70.
  • Patients on Crestor had a high-density lipoprotein (HDL) level of 50 milligrams per deciliter, compared to 49 for those who took Lipitor.

Nehal Mehta, a cardiologist with the University of Pennsylvania’s School of Medicine, says there’s no way to know if such a small change actually matters, in terms of preventing heart attacks and saving lives. And relatively few patients would even benefit that much. Only about 20% of patients are taking such high doses — 40 milligrams daily of Crestor or 80 milligrams daily of Lipitor, says Mehta, who wasn’t involved in the study.

Such minor differences in cholesterol levels are unlikely to affect heart disease risk, Patterson says. “The bottom line is that there isn’t a difference” between drugs,” he says. “You should make your decision on other factors, like which one is least expensive.”

About Lipitor and Crestor

Cholesterol medications are the leading class of prescription drugs in the USA, with 255 million prescriptions a year. Lipitor — the country’s best-selling drug, with sales of $7.2 billion last year — will be available as a generic Dec. 1, at a fraction of its current cost. Patterson says there will be no reason for insurance plans to pay for Crestor — the eighth-leading drug in the USA, with $3.8 billion in annual sales. In fact, by next month, nearly all statins will be available generically. Generics now account for 78% of all retail prescriptions sold, according to IMS Health.

Therapeutic Alternatives

June 02, 2009 By: PharmaSueAnn Category: Medtipster, Prescription Savings

What is a Therapeutic Alternative and How do they work with the $4 Type Discount Programs?

Let’s start from the beginning, therapeutic alternatives are drugs that provide the same effect but are chemically different from one another. If you are considering a therapeutic alternative to your current medication you will need to discuss the change with your doctor and get a new prescription.

Many brand name drugs have therapeutic alternatives available. In reviewing the Top 50 prescribed drugs many were identified as having possible therapeutic alternatives.

Example of brand name drugs with generic therapeutic alternatives – some of the alternatives are available on the $4 Discount Programs:

Lexapro
Lipitor
Nexium
Prevacid
Crestor
Valtrex
Fosamax
Zyrtec
Aciphex
Coreg
Imitrex Oral
Ambien
Nasonex
Actonel

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